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Index > Protein center > Slc1a2(Gene name) > Rat
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  • Slc1a2 (Gene name),
  • Excitatory amino acid transporter 2 (Protein name ),  EAA2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc1a2(Eaat2;Glt1);
    Protein name:
    Excitatory amino acid transporter 2;
    Alternative:
    Sodium-dependent glutamate/aspartate transporter 2(GLUT-R);GLT-1;Solute carrier family 1 member 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homotrimer (By similarity). Interacts with JUB.
    Function:
    Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    573
    Sequence:
    50:
    MASTEGANNM | PKQVEVRMHD | SHLSSEEPKH | RNLGMRMCDK | LGKNLLLSLT | 
    100:
    VFGVILGAVC | GGLLRLAAPI | HPDVVMLIAF | PGDILMRMLK | MLILPLIISS | 
    150:
    LITGLSGLDA | KASGRLGTRA | MVYYMSTTII | AAVLGVILVL | AIHPGNPKLK | 
    200:
    KQLGPGKKND | EVSSLDAFLD | LIRNLFPENL | VQACFQQIQT | VTKKVLVAPP | 
    250:
    SEEANTTKAV | ISLLNETMNE | APEETKIVIK | KGLEFKDGMN | VLGLIGFFIA | 
    300:
    FGIAMGKMGE | QAKLMVEFFN | ILNEIVMKLV | IMIMWYSPLG | IACLICGKII | 
    350:
    AIKDLEVVAR | QLGMYMITVI | VGLIIHGGIF | LPLIYFVVTR | KNPFSFFAGI | 
    400:
    FQAWITALGT | ASSAGTLPVT | FRCLEDNLGI | DKRVTRFVLP | VGATINMDGT | 
    450:
    ALYEAVAAIF | IAQMNGVILD | GGQIVTVSLT | ATLASIGAAS | IPSAGLVTML | 
    500:
    LILTAVGLPT | EDISLLVAVD | WLLDRMRTSV | NVVGDSFGAG | IVYHLSKSEL | 
    550:
    DTIDSQHRMH | EDIEMTKTQS | VYDDTKNHRE | SNSNQCVYAA | HNSVVIDECK | 
    573:
    VTLAANGKSA | DCSVEEEPWK | REK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Excitatory amino acid transporter 2
    Cat.:
    E15494r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Excitatory amino acid transporter 2
    Cat.:
    E15494h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Excitatory amino acid transporter 2
    Cat.:
    E15494m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Excitatory amino acid transporter 2
    Cat.:
    U15494h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Excitatory amino acid transporter 2
    Cat.:
    U15494m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Excitatory amino acid transporter 2
    Cat.:
    U15494r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat Excitatory amino acid transporter 2
    Cat.:
    P15494Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Excitatory amino acid transporter 2
    Cat.:
    P15494Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Excitatory amino acid transporter 2
    Cat.:
    P15494Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Excitatory amino acid transporter 2
    Monoclonal Antibody for Rat Excitatory amino acid transporter 2
    Monoclonal Antibody for Rat Excitatory amino acid transporter 2
    Protein for Rat Excitatory amino acid transporter 2
    Protein for Rat Excitatory amino acid transporter 2
    Protein for Rat Excitatory amino acid transporter 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    3. 3.
      "Glutamate transporters from brain. A novel neurotransmitter transporter family."
      Kanner B.I.
      FEBS Lett.325:95-99(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 260-289
    4. 4.
      Roginski R.S. , Choudhury K. , Meiners S. , Marone M. , Basma A.N. , Geller H.M.
      Submitted (1995-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Forebrain.
    5. 5.
      "The rat hepatoma cell line H4-II-E-C3 expresses high activities of the high-affinity glutamate transporter GLT-1A."
      Pollard M. , McGivan J.
      FEBS Lett.484:74-76(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM GLT-1A)
      tissue: Hepatoma.
    6. 6.
      Lubec G. , Kang S.U.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 158-173;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Brain.
    7. 7.
      "Histidine 326 is critical for the function of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain."
      Zhang Y. , Pines G. , Kanner B.I.
      J. Biol. Chem.269:19573-19577(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF LYS-298 AND HIS-326
    8. 8.
      "The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba."
      Marie H. , Billups D. , Bedford F.K. , Dumoulin A. , Goyal R.K. , Longmore G.D. , Moss S.J. , Attwell D.
      Mol. Cell. Neurosci.19:152-164(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AJUBA
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